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Microarray Scanner - MBI Innoscan AutoLoader 1100AL

Catalog Number:
MBIIS1100-AL
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MBI Innoscan AutoLoader 1100, Confocal Fluorescence Scanner with computer

Combining ultra-high resolution and high-level automation, the InnoScan 1100 AL is perfect for fast, whole slide imaging. With three excitation wavelengths, it is ideal for reading cell microarrays as well as classic three-color microarrays.

 

General description

Characterized by its ease of use, performance and versatility, the InnoScan 1100 AL is the ideal tool for cell microarrays as well as three color microarrays.

  • High quality images: With a resolution of up to 0.5µm/pixel or a 20x objective equivalent, the InnoScan 1100 AL is the highest resolution microarray scanner on the market. This combined with a real time autofocus system and confocal PMT detection, the InnoScan 1100 AL provides high-quality images for detailed analysis of your microarrays.

  • Easy automation: Provided with a user-friendly image acquisition software and 24-slide autoloader, the InnoScan 1100 AL is capable of fully automated scanning of 24 slides at a time.

  • Multiplexed whole slide imaging: The InnoScan 1100 AL is capable of scanning any microscope slide with various substrates: cells, tissue, proteins, DNA, glycans, peptides and others. Equipped with three excitation channels, it empowers users with more multiplexing capabilities, thus allowing the analysis of several samples or markers on the same slide.

 

Applications

The InnoScan 1100 AL is the ideal tool for fast and automated whole-slide imaging:

  • Cell Microarrays: MicroEnvironment arrays, peptide/HLA microarrays, reverse transfection arrays…
  • Tissue Immunofluorescence
  • Three color microarrays
  • High density microarrays

 

In the following application fields :

  • Cell and tissue imaging
  • Glycomics: glycan arrays
  • Proteomics: peptide arrays
  • Biomarkers and disease stratification
  • Food Industry
  • Pharmaceutical Industry

 

Technology

The InnoScan 1100 is a confocal scanner equipped with 3 excitation lasers (488, 532 and 635nm) which are coupled with 3 extremely sensitive photomultiplier tubes (PMT) which allow whole-slide image acquisition. The PMTs are linear over the entire dynamic range (from 1% to 100%) making it easy for the user to set PMT gain for the perfect adjustment of the fluorescence signal levels to avoid saturation.

The InnoScan 1100 has the highest resolution on the market (up to 0.5µm/pixel) and uses a real-time autofocus system which adapts to substrate distortion, thus making the entire reading area completely uniform.

The InnoScan scanners are industry renowned for their excellent photometric properties, particularly in terms of sensitivity and signal-to-noise ratio.

Thanks to Extended Dynamic Range mode (XDR), InnoScan scanners have a dynamic range of over 106 and are thus capable of detecting the weakest signals while avoiding saturated spots.

 

InnoScan 1100 AL

LOADER CAPACITY 24 slides
DIMENSIONS (LXDXH) 322 x 656 x 439 mm3 - 12.7” x 25.8” x 17.3”
WEIGHT 35 kg (77.1 lbs)

 

InnoScan 1100

PIXEL SIZE 0.5 - 40μm
LASER EXCITATION WAVELENGTH 488nm 532nm 635nm
COMPATIBLE FLUOROPHORES* Cy2, FITC
Alexa Fluor 458, Alexa Fluor 488
Cy3
Alexa Fluor 544, Alexa Fluor 555
Cy5, DRAQ 5 Alexa Fluor 647
LASER POWER Adjustable (2 laser powers)
LOADER CAPACITY 1 slide
DETECTION TYPE Real-time confocal with 3 analog photomultipliers (PMT)
PMT GAIN Adjustable from 0 to 100%
(Linear from 1 to 100%)
OPTICAL FILTER 7 position filter wheel**
1 standard fluorescence and 1 neutral density filter per channel;5 additional filters on request
FOCUS Real-time autofocus
Manual focus: offset adjustment 300 μm range, 1 μm increment
SLIDE SIZE Compatible with all standard microscope slides: 25-26 x 75-76 mm2 / 1” x 3” ; thickness: 0.9 - 1.2 mm
SCANNING AREA Adjustable up to 22 x 74 mm2
SCANNING SPEED From 10 to 35 lines/second (l/s)
3.6 minutes per slide at 10 μm and 10.5min for an area 22x22 mm2 at 1μm
DYNAMIC RANGE > 104 in normal mode or > 106 in dynamic extension mode
UNIFORMITY > 95%
BARCODE READER Automatic barcode reading
INTERFACE Ethernet interface
IMAGE FORMAT TIFF (16-bit and 20-bit in dynamic extension mode)
POWER SUPPLY ~ 100-240 VAC, 1.2 A, 50-60 Hz
ACQUISITION SOFTWARE MAPIX (image acquisition and spot quantification software)
DIMENSIONS (LXDXH) 316 x 549 x 432 mm3 12.5” x 21.6” x 17.0”
WEIGHT 30 kg (66.1 lbs)
More Information
Resolution from 0.5 to 40 µm/pixel
Excitation wavelength 488nm, 532nm and 635nm
Scanning speed 20 to 35 lines/sec. (25 lines/sec. max for 0.5µm pixel size) 3.5 minutes to scan a whole slide at a 10 µm/pixel and 3 colors 10.5 min. for an area of 22 x 22 mm2 at 1 µm/pixel and 3 colors
Scanning area 22 x 74 mm^2
Dynamic range (linearity) 10^6
Laser Laser diode, adjustable (2 laser power available)
Gain PMT Linear from 0 to 100 % (step 0.1 from 0.1 to 1% and 1 from 1 to 100%)
Autofocus Automatic or manual
Detection Analog PMT confocal detection
Chip Format Standard microscope slides norm ISO 8037-1 25 x 77 mm2 (1" x 3’’)
Interface ethernet
Image format 16-bit and 20-bit TIFF
Sample All standard microscope slide 25 x 75mm^2 / 1 x 3 "
Barcode reader Yes
Dimensions 33 x 66 x 44 cm (13” x 26” x 17.3”)
Net Weight 35 Kg (77.16lbs)
Option: Autoloader software Total integration in the MAPIX software coming with the Innoscan Scanners
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Brochure (1.17 MB)
Mapix_Software (867.73 kB)