Microarray Scanner - MBI Innoscan AutoLoader 1100AL
MBI Innoscan AutoLoader 1100, Confocal Fluorescence Scanner with computer
Combining ultra-high resolution and high-level automation, the InnoScan 1100 AL is perfect for fast, whole slide imaging. With three excitation wavelengths, it is ideal for reading cell microarrays as well as classic three-color microarrays.
General description
Characterized by its ease of use, performance and versatility, the InnoScan 1100 AL is the ideal tool for cell microarrays as well as three color microarrays.
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High quality images: With a resolution of up to 0.5µm/pixel or a 20x objective equivalent, the InnoScan 1100 AL is the highest resolution microarray scanner on the market. This combined with a real time autofocus system and confocal PMT detection, the InnoScan 1100 AL provides high-quality images for detailed analysis of your microarrays.
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Easy automation: Provided with a user-friendly image acquisition software and 24-slide autoloader, the InnoScan 1100 AL is capable of fully automated scanning of 24 slides at a time.
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Multiplexed whole slide imaging: The InnoScan 1100 AL is capable of scanning any microscope slide with various substrates: cells, tissue, proteins, DNA, glycans, peptides and others. Equipped with three excitation channels, it empowers users with more multiplexing capabilities, thus allowing the analysis of several samples or markers on the same slide.
Applications
The InnoScan 1100 AL is the ideal tool for fast and automated whole-slide imaging:
- Cell Microarrays: MicroEnvironment arrays, peptide/HLA microarrays, reverse transfection arrays…
- Tissue Immunofluorescence
- Three color microarrays
- High density microarrays
In the following application fields :
- Cell and tissue imaging
- Glycomics: glycan arrays
- Proteomics: peptide arrays
- Biomarkers and disease stratification
- Food Industry
- Pharmaceutical Industry
Technology
The InnoScan 1100 is a confocal scanner equipped with 3 excitation lasers (488, 532 and 635nm) which are coupled with 3 extremely sensitive photomultiplier tubes (PMT) which allow whole-slide image acquisition. The PMTs are linear over the entire dynamic range (from 1% to 100%) making it easy for the user to set PMT gain for the perfect adjustment of the fluorescence signal levels to avoid saturation.
The InnoScan 1100 has the highest resolution on the market (up to 0.5µm/pixel) and uses a real-time autofocus system which adapts to substrate distortion, thus making the entire reading area completely uniform.
The InnoScan scanners are industry renowned for their excellent photometric properties, particularly in terms of sensitivity and signal-to-noise ratio.
Thanks to Extended Dynamic Range mode (XDR), InnoScan scanners have a dynamic range of over 106 and are thus capable of detecting the weakest signals while avoiding saturated spots.
InnoScan 1100 AL
| LOADER CAPACITY | 24 slides |
| DIMENSIONS (LXDXH) | 322 x 656 x 439 mm3 - 12.7” x 25.8” x 17.3” |
| WEIGHT | 35 kg (77.1 lbs) |
InnoScan 1100
| PIXEL SIZE | 0.5 - 40μm | ||
| LASER EXCITATION WAVELENGTH | 488nm | 532nm | 635nm |
| COMPATIBLE FLUOROPHORES* | Cy2, FITC Alexa Fluor 458, Alexa Fluor 488 |
Cy3 Alexa Fluor 544, Alexa Fluor 555 |
Cy5, DRAQ 5 Alexa Fluor 647 |
| LASER POWER | Adjustable (2 laser powers) | ||
| LOADER CAPACITY | 1 slide | ||
| DETECTION TYPE | Real-time confocal with 3 analog photomultipliers (PMT) | ||
| PMT GAIN | Adjustable from 0 to 100% (Linear from 1 to 100%) |
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| OPTICAL FILTER | 7 position filter wheel** 1 standard fluorescence and 1 neutral density filter per channel;5 additional filters on request |
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| FOCUS | Real-time autofocus Manual focus: offset adjustment 300 μm range, 1 μm increment |
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| SLIDE SIZE | Compatible with all standard microscope slides: 25-26 x 75-76 mm2 / 1” x 3” ; thickness: 0.9 - 1.2 mm | ||
| SCANNING AREA | Adjustable up to 22 x 74 mm2 | ||
| SCANNING SPEED | From 10 to 35 lines/second (l/s) 3.6 minutes per slide at 10 μm and 10.5min for an area 22x22 mm2 at 1μm |
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| DYNAMIC RANGE | > 104 in normal mode or > 106 in dynamic extension mode | ||
| UNIFORMITY | > 95% | ||
| BARCODE READER | Automatic barcode reading | ||
| INTERFACE | Ethernet interface | ||
| IMAGE FORMAT | TIFF (16-bit and 20-bit in dynamic extension mode) | ||
| POWER SUPPLY | ~ 100-240 VAC, 1.2 A, 50-60 Hz | ||
| ACQUISITION SOFTWARE | MAPIX (image acquisition and spot quantification software) | ||
| DIMENSIONS (LXDXH) | 316 x 549 x 432 mm3 12.5” x 21.6” x 17.0” | ||
| WEIGHT | 30 kg (66.1 lbs) | ||
| Résolution | from 0.5 to 40 µm/pixel |
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| Longueur d'onde d'excitation | 488nm, 532nm and 635nm |
| Vitesse de scan | De 20 à 35 lignes par seconde (25 lignes par seconde maximum pour une taille de pixel de 0,5 µm). 3,5 minutes pour numériser une lame entière à 10 µm/pixel et 3 couleurs. 10,5 minutes pour une zone de 22 x 22 mm² à 1 µm/pixel et 3 couleurs. |
| Surface de scan | 22 x 74 mm^2 |
| Plage dynamique (Linéarité) | 10^6 |
| Laser | Diode laser, réglable (2 puissances laser disponibles) |
| Gain PMT | Linéaire de 0 à 100 % (par pas de 0,1 de 0,1 à 1 %, et de 1 de 1 à 100 %). |
| Autofocus | Automatique ou manuel |
| Detection | Analyse confocale à photomultiplicateur analogique (PMT) |
| Format des puces | Lames de microscope standard norme ISO 8037-1 25 x 77 mm² (1" x 3’’) |
| Interface | ethernet |
| Format d'image | TIFF 16 bits et TIFF 20 bits |
| Lames d'échantillon | Toutes lames de microscope standard de 25 x 75 mm ^ 2/1 x 3 " |
| Lecteur de code-barre | Oui |
| Dimensions | 33 x 66 x 44 cm (13” x 26” x 17.3”) |
| Poids net | 35 Kg (77.16lbs) |
| Optionnel : Logiciel du cahrgeur automatique | Intégration totale dans le logiciel MAPIX venir avec le Innoscan Scanners |
