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qTOWER³ auto Series - Real-time PCR Meets Automation

qTOWER³ auto Series - Real-time PCR Meets Automation

  • High-end qPCR solution for automated research
  • Sophisticated, automation-friendly design with reduced footprint
  • Smooth integration into computer-controlled workflows
  • Compatibility to common plates handlers and automation systems

 

The qTOWER³ auto is the go-to solution for robotic qPCR workflows. The system combines Analytik Jena’s patented optical technology, Biometra´s proven thermal cycler technology, user convenience, data integrity and unique adaptability. It is ideal for routine labs looking to increase throughput, reliability and quality of their qPCR results for applications like genotyping, genomic profiling, biomarker analysis or drug discovery.

 

Streamlining Workflows Through Automation

Based on lab automation demands, the qTOWER³ auto with its decoupled power module and a freely accessible sample plate tray offers a reduced footprint. In developing the system, special emphasis was placed on compatibility with the common manufacturers of robot arms and automation systems. The unique, motorized plate lifter system simplifies workflows by allowing gentle lifting of the sample plate to release it safely from the sample block, while the innovative labware detection function reliably detects any improper sample plate loading. Discover our solution to provide you with confidence in your system and free up resources to focus on value-adding activities.

  • Modular design to fit on nearly all benchtops
  • Compatibility to common plates handlers and automation systems
  • Free access to the sample plate tray
  • Maximum workflow security through a unique labware detection function
  • Plate lifter system ensures an easy loading and unloading of the sample plate

 

Scalable Solutions According to Throughput Needs

Optimize your qPCR workflow and reduce your costs without compromising reliability and data quality. With qTOWER³ auto, a compact, automatable real-time PCR thermal cycler, even high sample numbers can be handled safely and cost-efficiently. The fast and sensitive analysis and quantification of DNA samples is reproducibly ensured by the excellent performance of the qTOWER³ auto, as it is based on the proven technology of the qTOWER³- family.

 

Technical Data

 

qTOWER³ auto 

qTOWER³ 84 auto 

Thermoblock

Silver sample block with gold coating

Aluminum, special alloy

Block capacity

96 well microplates with optical foil (verified for automation processes, full-skirted) 

384 well microplates with optical foil (verified for automation processes, full-skirted) 

Sample volume

5 – 100 µL 

2 – 30 µL (5 – 20 µL recommended) 

Heating

Max. 8 °C/second 

Max. 4 °C/second  

Cooling

Max. 5.5 °C/second

Max. 2 °C/second  

Block exchange

No

Number of blocks 1
Block technology  High-power peltier elements 
Standby temperature  Possible, down to 4 °C 
Temperature control mode 
  • Block Control 

  • Tube Control  

Temperature setting range

4 °C to 99 °C 

Temperature uniformity

55 ° ± 0.15 °C after 15 seconds 

Temperature control precision

± 0.1 °C
Temperature increments  Min. 0.1 ° C / cycle 
Time increments  Min. 1 sec / cycle 
Display  No
Software  PC control with qPCRsoft auto 
Interfaces  USB for PC connection or Ethernet for the connection with the external power module 
Dimensions (W × H × L) 

310 × 479 × 365 mm (Drawer closed) 
310 × 479 × 477 mm (Drawer open) 

Traveling distance of drawer  112 mm 
Position tolerance of the sample plate when the drawer is moved out   ± 0.15 mm
Noise emission  Max. 45 dB 
Weight  Approx. 27 kg 

Contact pressure

30 kg, automated

Lid temperature

30 °C – 110 °C
Safety features 
  • Sample chamber is monitored by sensors 

  • Overheating protection in the heated lid 

  • Interlock switch (drawer) 

Warranty 
  • 2 years warranty on device system  

  • 10-year long-term warranty on high performance optics 

Optics

Measuring principle

Fiber optic shuttle system with 8 optical fibers  Fiber optic shuttle system with 16 optical fibers 

Light source

longlife, high-power LEDs (RGBW)  4 longlife, high-power LEDs (RGBW) 

Detector

Highly sensitive PMT (Photo Multiplier Tube) Highly sensitive PMT (Photo Multiplier Tube) 

Readout time

6 seconds for 96 wells independent of the number of dyes  6 seconds for 384 wells independent of the number of selected dyes 
Wavelenght range  Excitation: 465 nm - 625 nm; Emission: 524 nm - 710 nm 

Color modules

  • 12 Color-, FRET- and Protein modules 

  • 6 positions inside device 

Configuration Preconfigured with four color modules 
Upgradability  Possible with service 

 

Technology Highlights for Automated real-time PCR

Harnessing optimized block technology

Powered by the proven Biometra block technology, the qTOWER³ auto sets new standards in terms of speed and homogeneity for automated real-time PCR. High-quality block materials and advanced Peltier technology ensure maximum thermal conductivity to enable rapid heating and cooling for shorter runtimes. This not only speeds up qPCR analysis, but provides superior accuracy and highest well-to-well reproducibility, while eliminating the cost of repeated qPCR runs and the loss of reagents and samples due to inaccurate temperatures.

  • Exceptional heating and cooling rates
  • Efficient, uniform temperature distribution
  • Outstanding and high-quality data accuracy
  • Variable reaction volumes

 

Maximum reliability through proven optical system

Excellent data quality of fluorescent measurements is achieved through the patented fiber optic detection system. It enables homogeneous illumination and readout of each individual well which results in reduced sample to sample variations for exact, meaningful results. Powered by a long-lasting LED light source, equipped with a sensitive Photo-multiplier tube detector and a finely tuned set of excitation and emission filters, it provides optimized excitation for each individual sample while detecting the emitted fluorescent signals with extraordinary homogeneity. The ability to change or retrofit color modules increases the flexibility in the choice of fluorescent dyes that can be used to perfectly meet your current and future requirements for multiplex applications.

  • Enhanced multi-target detection capabilities
  • Retrofitting of filter modules
  • Calibration free optical unit
  • Broad dynamic range
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