MYCN gene amplification detection probe (N-MYC/LAF4)

MYCN Gene Amplification Probe Detection Kit - 100µL/10 Tests

MYCN (MYCN Proto-Oncogene, BHLH Transcription Factor) gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014].

Product Introduction
This kit uses Orange Fluorescein labeled N-MYC probe and Green Fluorescein labeled LAF4, to combine N-MYC/LAF4 genes with the target site by in situ hybridization.

Product Main Components

The kit consists of N N-MYC/LAF4 dual color probe

Applicable Instruments

Fluorescence microscopy imaging systems, including fluorescence microscopy and filter sets suitable for DAPI (367/452), Green (495/517), and Orange (547/565).