13q gene detection probe (RB1/13q34)

13q [RB1/13q34 (RB1/LAMP1)] Probe Detection Kit (Fluorescence In-Situ Hybridization Method)  - 100µL/10 Tests

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]. 

Product Introduction
The kit uses orange fluorescein-labeled RB1(13q14) probe and green fluorescein-labeled 13q34(LAMP1) probe to bind the MLL probe to the target detection site by in situ hybridization.

Product Main Components

The kit consists of RB1/13q34 dual-color probe

Applicable Instruments
Fluorescence microscopy imaging systems, including fluorescence microscopy and filter sets suitable for DAPI (367/452), Green (495/517), and Orange (547/565).