Your personal ELISA automation. Crocodile is a compact, fully automated, high performance ELISA workstation for low to medium throughput.
Under normal circumstances, running your ELISA assays required an hour and more of your attention. It was hard to plan other important activities while your assay was in process. Crocodile provides the same functionality as four individual instruments in a footprint similar to a standard stand-alone reader. The use of Crocodile will reduce assay times by eliminating the need to move plates between dispenser, washer, incubator and shaker. This allows you to perform other important activities and be even more productive.
Key Features & Benefits
A compact workstation that fits anywhere
Crocodile is only 26.5 cm wide. With all reagent bottles placed to the left of the instrument, it requires no more than 40 cm of bench space – the width of a typical ELISA reader.
Walk away automation
The workstation is designed for truly unattended operation. Simply insert the sample microplate which includes standards and samples, choose the assay protocol and leave the work to Crocodile.
Easy hardware setup
All functional modules are housed in one compact box. Connect the unit with the power outlet and a notebook or desktop computer. The tubing for wash and waste liquids is preinstalled, ready to be introduced into the wash and waste bottles.
Fast start
In everyday use, preparing to use Crocodile won't give you any headaches. Wash, waste, and reagent bottles are readily accessible, right next to the instrument. The instrument requires minimal startup time.
Easy maintenance and reliable service
After every use, simply flush the tubing system. You will find that, as with all liquid handling instruments, the tubing system must be replaced from time to time. Accessing the required components and parts is very easy. Trained technical staff is available to help if needed, and after-warranty service agreements are available in most geographical locations – to ensure troublefree operation over the lifetime of the instrument.
An open system
Crocodile will adapt to any ELISA format; including sandwich, competitive, or other. Reagent bottles of any shape and size are accommodated by the carefully designed and tested bottle holders.
Validation made easy
Many labs regularly validate the performance of the instruments which generate measurement data. For Crocodile, this task is supported by our 3Q Package: Installation Qualification, Operation Qualification and Performance Qualification steps are performed according to detailed instructions provided. The results are documented in checklists according to the specific features of the instrument.
Regulatory compliance
Crocodile has been developed according to the most stringent regulations in the industry: DIN ISO 13485. Every step was accompanied by thorough risk analysis. Selection of raw materials and the assembly process is performed under strict observation of released procedures and processes. After final assembly, every individual unit has undergone several days of extensive testing and will be accompanied by a certificate of analysis stating compliance with specifications.
PC-Software
The user friendly software adapts to any ELISA protocol easily. The four different functions can be aligned in any sequence, one or several times each (for example one to four dispensing steps or multiple washing steps). Setting of each step is flexible and intuitive. Once you have chosen an assay protocol, the screen will show a graphic of the entire assay schedule, as it will be performed by Crocodile.
TECHNICAL DETAILS
Dispenser
Type
4 independent precision pumps
Volume Range
10-2000 µL
Precision
<2% CV at 100 µL
Accuracy
<5% at 100 µL
Reagent support
Any bottle or vial type can be attached
Washer
Manifold configuration
Autoclavable 8-way manifold with 2 parallel needles
Dispense volume
25-1000 µL
Wash modes
Standard, Overflow, Soak, Two-Point, Sweep
Wash buffer capacity
3 x 1 L bottles for different wash solutions
Waste liquid container
2 L bottle
Incubators
Temperature range
From ambient +4° C to 55° C
Temperature stability
±1° C across plate at 37° C
Incubation time
Programmable
Temperature monitoring
Yes
Shaker
Shaking
Independent linear motion 5-20 Hz
Software
Software
Crocodile Control Software for protocol creation and running
Optional: Mikrowin for advanced curve fitting data evaluation, easy automation and compliance with CFR 21 part 11
General Specifications
Sample format
1 x 96-well microplate (ANSI SLAS)
Power supply
Desktop power supply and power cord. Input 110-240 V AC, output 24 V/3.3 A DC
Dimensions (W x D x H)
263 x 626 x 258 mm
Weight
14.8 kg
Interface
USB
Operating temperature
10-35° C
Humidity
Up to 75% (non-condensing)
Montreal Biotech Inc. Quality Laboratory Equipment for Research & Industry www.montreal-biotech.com
