FUS (FUS RNA Binding Protein) gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009].
Product Introduction
This kit uses Orange fluorescein and Green fluorescein to label FUS. FUS probe can be bound to the target detection site by in situ hybridization.
Product Main Components
The kit consists of FUS dual color probe
Component name
Specifications
Quantity
Main components
FUS dual color probe
100μL/Tube
1
FUS orange probe ; FUS green probe
Applicable Instruments
Fluorescence microscopy imaging systems, including fluorescence microscopy and filter sets suitable for DAPI (367/452), Green (495/517), and Orange (547/565).