TFE3 gene break apart detection probe (TFE3)
TFE3 Gene Break Apart Probe Detection Kit - 100µL/10 Tests
TFE3 (Transcription Factor Binding To IGHM Enhancer 3) gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. [provided by RefSeq, Aug 2013].
Product Introduction
This kit uses Orange fluorescein labeled TFE probe and Green fluorescein labeled TFE, to combine TFE gene with the target site by in situ hybridization.
Product Main Components
The kit consists of TFE dual color probe
|
Component name |
Specifications |
Quantity |
Main components |
|
TFE3 dual color probe |
100μL/Tube |
1 |
TFE3 Orange probe ; TFE3 Green probe |
Applicable Instruments
Fluorescence microscopy imaging systems, including fluorescence microscopy and filter sets suitable for DAPI (367/452), Green (495/517), and Orange (547/565).