The EVE-HT is a high-throughput automated multiple cell counter designed for rapid, accurate cell line analysis. Processing up to 48 samples simultaneously in under 3 minutes, it delivers total count, live count, and viability measurements using standard trypan blue staining with minimal user-to-user variation. An optional 21 CFR Part 11 compliance module makes it suitable for regulated GMP environments.
Key Highlights: 48 samples in < 3 minutes • 20 µL sample volume per channel • Trypan blue viability measurement • Advanced declustering algorithm for clumped cells • High instrument-to-instrument precision • High correlation to hemocytometer • Optional 21 CFR Part 11 / GMP-ready module • User-friendly interface with automated acquisition
Core Features
High-Throughput 48-Sample Batch Processing
The counting plate contains 48 channels, enabling measurement of 48 samples in a single 3-minute run. Boost cell line screening efficiency and eliminate bottlenecks in high-volume workflows.
Small Sample Volume
Requires only 20 µL of sample per channel. Save valuable cells while maintaining accurate and precise counting results even with limited material.
Advanced Declustering Algorithm
Proprietary software recognizes and counts individual cells within clumps. Distinguishes aggregated cells based on size and shape, excludes debris, and delivers accurate counts for irregularly shaped and clumped cell lines.
Accurate and Precise Results
Automated image acquisition and proprietary image analysis quantify cell numbers and viabilities with little user-to-user variation. Demonstrates high multi-instrument precision for CHO cells and strong correlation to traditional hemocytometer counts across low, medium, and high concentrations.
21 CFR Part 11 / GMP-Ready Compliance (Optional)
The optional 21 CFR Part 11 module safeguards all records and data in compliance with FDA requirements. Features include:
User management and role-based access control
Electronic records and electronic signatures
Complete audit trail logging every action with date, time, and user details
Data modification restricted to authorized users only
Technical Specifications
Specification
Details
SKU / Cat. No.
EVE-HT
Channels
48
Analysis Time
< 3 minutes / 48 tests
Loading Sample Volume
20 µL / channel
Measuring Volume
0.4 µL / test
Concentration Range (Detectable)
1 × 10⁴ – 2 × 10⁷ cells/mL
Concentration Range (Optimal)
1 × 10⁵ – 1 × 10⁷ cells/mL
Cell Size Range (Detectable)
1 – 85 µm
Cell Size Range (Optimal)
5 – 80 µm
Staining Dye
Trypan blue stain
21 CFR Part 11
Optional compliance module available
Operating System
Windows 10
Dimensions (W × D × H)
586 × 477 × 458 mm
Net Weight
40 kg
Power
100–240 V~, 50/60 Hz
Applications
High-throughput cell line screening and monitoring
Bioprocess development and media optimization
CHO cell and other eukaryotic cell culture analysis
Regulated GMP manufacturing with optional 21 CFR Part 11 compliance
Quality control and release testing for cell-based products