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MBI InnoQuant - A New Standard in Fluorescence Slide Imaging

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InnoQuant
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MBI InnoQuant - A New Standard in Fluorescence Slide Imaging

Beyond Widefield. Without Confocal Constraints.

MBI InnoQuant is the only fluorescence slide scanner with confocal capabilities. It is designed for fast and quantitative imaging of full tissue sections.

MBI InnoQuant combines single-pass scanning, simultaneous 4-channel acquisition, and PMT-based detection to deliver sharp, reproducible fluorescence data — without stitching, shading correction, or post-processing. With dynamic focusing, TIFF multi-resolution output, and full automation, MBI InnoQuant bridges the gap between widefield and confocal microscopy, offering unmatched speed and consistency for multiplexed tissue analysis.

Whether you're working in neuroscience, oncology, or translational research, MBI InnoQuant brings you the image quality and data integrity needed to scale up your whole-slide fluorescence imaging — reliably and efficiently.

How is it different from other slide scanners?

What sets the MBI InnoQuant system apart from its counterparts is its seamless operation. Bid farewell to the time-consuming task of tracking down samples or adjusting focus manually; the software takes care of it all. With swift and continuous scanning, there's no need for stitching or tiling. The result? Your sample is recorded and stored as a single, homogeneous image. The MBI InnoQuant system offers both a single-slide version and an autoloader version, catering to high-throughput experiments with the capacity to handle up to 24 slides.

Speed and Quality

Speed comparison chart

Superior Quality / Time ratio

4 colors simultaneous multiplexing

Only 10 minutes for a mouse brain coronal section
Focus and saving included

  • 0.5 µm/pixel
  • 0.7 µm (lateral resolution)
  • 20x equiv. magnification

20x magnification

Adjustable pixel size

  • 0.5 NA
  • 0.7 µm lateral resolution
  • 3 µm axial resolution

Fluorescence instrument

No exposure time

  • Simultaneous 4-color imaging
  • Scanning time independent of staining intensities!

Tile free

Quantitative raw data, without artifacts

  • Line-by-line laser scanning
  • No field of view limits
  • 16-bit digitization

2D scanner with automated focus map — Dynamic by-content focus for 2D images

Ensuring Reproducible Results: MBI InnoQuant with Argolight Metrology Slide

Argolight metrology slide

In scientific imaging, reproducibility and precision are everything. To generate highly quantitative and consistent data, you need complete confidence in your instrument.

That's where MBI InnoQuant shines — delivering exceptional field uniformity and stable laser excitation for reliable fluorescence slide scanning. But how can you ensure consistent results over time, or between different MBI InnoQuant units?

To address this, we've partnered with Argolight, a leader in precision metrology. Argolight manufactures specialized metrology slides designed to monitor and maintain the performance of imaging systems.

Each MBI InnoQuant comes equipped with an Argolight metrology slide. With a quick "Check Scanner" procedure, you can verify in just 10 minutes that your MBI InnoQuant is performing exactly as it did when it left our factory — ensuring long-term reliability and reproducibility.

Discover how MBI InnoQuant fluorescence slide scanner captures high-resolution, multiplexed tissue data in just one scan.

ClickBrain section #1 ClickBrain section #2 Click Brain section #3 ClickTonsil section

Multiplexing without Spectral Crosstalk

Multiplexing diagram

4-Lasers Excitation

Synchronous detection (4 parallel tracks)

  • 375 nm
  • 488 nm
  • 561 nm
  • 640 nm

Spatial demultiplexing
Clean separation between excitation spots

Multiplexing detail

Technical Specifications

MBI InnoQuant Configuration
Laser Excitation 375 nm488 nm561 nm640 nm
6 additional filter positions per PMT available
Emission Filters FF01-440/40 • FF01-513/17 • FF01-593/40 • FF01-680/42
Detection 4 independent PMTs • Linear gain 0.01-100%
Scanning Performance 17 min for 18×18 mm @ 0.5 µm
Pixel size: 0.5 - 40 µm adjustable • Max area: 26×76 mm
Slide Capacity Single slide or 24-slide autoloader • Standard 26×76 mm slides (up to 1.8mm thick)
Dimensions & Weight 429×696×521 mm (W×D×H) • 52 kg
Power: 100-240VAC, 1.2A, 50-60Hz • Auto barcode reader included
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Compatible with 3rd party analysis software

More Information
Resolution from 0.5 to 40 µm/pixel
Excitation wavelength 375 nm, 488 nm, 561 nm and 640 nm
Scanning speed 17 min for a scan area of 18 x 18 mm / 0.70 x 0.70 inch at pixel size 0.5 µm
Scanning area Adjustable up to 26 x 76 mm/ 1 x 3 inch
Gain PMT Linear from 0.01 to 100%
Autofocus 3 different focus options Fully automated in-content focus; Real-time autofocus; Fixed focus
Detection 4 independent photomultipliers (PMT)
Image format Non-proprietary image format (multi-resolution TIFF)
Sample Compatible with standard microscope slides: 26 x 76 mm / 1 x 3 inch Maximal thickness 1.8 mm / 0.07 inch
Barcode reader Yes
Dimensions (W) 16.88 x (D) 27.40 x (H) 20.51
Net Weight 52 kg
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